Search on: A-KINASE ANCHOR PROTEINS 
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Descriptor English:   A Kinase Anchor Proteins 
Descriptor Spanish:   Proteínas de Anclaje a la Quinasa A 
Descriptor Portuguese:   Proteínas de Ancoragem à Quinase A 
Synonyms English:   A-Kinase Anchor Proteins
Protein Kinase A Anchor Proteins
Anchor Proteins, A-Kinase  
Tree Number:   D12.644.360.024.065
D12.776.157.057.003
D12.776.476.024.069
Definition English:   A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   52783 
Unique Identifier:   D054758 

Occurrence in VHL:
 

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